Biochemistry of Multimolecular Complexes

Biological systems depend on multimolecular complexes to accomplish the tasks. While these complexes can be large and may comprise several tens of components, the present imaging techniques are limited to imaging only two or three independent components of a molecular complex that can be 8-10 nm in diameter. Isolation of multimolecular complexes while retaining their supramolecular interactions has been critical to the study of mitochondrial respiratory supercomplexes.

  • Multienzyme complexes
  • Multiprotein complex
  • Protein-fatty acid complexes
  • Ubiqutin Proteasome Pathway

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