B.Yuvaraj
Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), India
Title: Association of serum Vitamin D levels with Bacterial load in Pulmonary Tuberculosis Patients
Biography
Biography: B.Yuvaraj
Abstract
Vitamin D is known to have diverse effects on various systems in the body. There is evidence to suggest that a link exists between the serum vitamin D status and tuberculosis. The present study was designed to assess the alterations in serum 25 hydroxy-vitamin D levels in newly diagnosed sputum AFB positive pulmonary tuberculosis patients and to study the association, if any, between serum vitamin D levels and different levels of sputum smear positivity. Serum 25 hydroxy-vitamin D levels were estimated in 65 sputum AFB positive pulmonary tuberculosis patients and 65 age and gender-matched healthy controls. The levels of serum 25 hydroxy-vitamin D in tuberculosis patients were not statistically different from levels in healthy controls. However among patients with pulmonary tuberculosis there was a significant negative correlation between the levels of serum 25 hydroxy-vitamin D and levels of sputum positivity. Serum vitamin D levels negatively correlates with bacterial load in patients with active pulmonary tuberculosis.